OPCPlus
OPCPlus
more information about OPC Plus
- High-quality grape seed extract, standardized to 95% polyphenols
- Additional camu camu extract for natural vitamin C
- Over 20 years of proven application
- Developed and supervised by physicians
- Gentle manufacturing process
- Hypoallergenic thanks to Biotikon special technology
- Vegan capsules free from PEG and carrageenan
- Highest food safety standards: HACCP & ISO 9001
- Sustainable, plastic-free shipping
- Your health is important to us
- Aluminum-free sealing
Shipping and Charges
Payment and Shipping
The following conditions apply:
Shipping conditions
Delivery of goods takes place worldwide.
Shipping costs (including statutory VAT)
Deliveries within Germany:
We charge a flat shipping fee of €5.00 per order.
For orders with a value of €70.00 or more, delivery is free of shipping charges.
Deliveries abroad:
We charge shipping costs abroad based on the order value (gross value of goods):
Zone 1:
• Switzerland, Austria, United Kingdom (GB), Germany and EU countries: Shipping is free for goods with a value of €70,- or more; otherwise €5,-.
Zone 2:
• Shipping is free for goods with a value of €200,- or more; otherwise €5,-.
Zone 3:
• Shipping is free for goods with a value of €400,- or more; otherwise €80,-.
Zone 4:
• Shipping is free for goods with a value of €500,- or more; otherwise €100,-
Zone 1 (EU) including Switzerland and United Kingdom (GB):
Belgium, Bulgaria, Denmark (except Faroe Islands, Greenland), Estonia, Finland (except Åland Islands), France (except overseas territories and departments), Greece (except Mount Athos), United Kingdom (GB, except Channel Islands), Ireland, Italy (except Livigno and Campione d'Italia), Croatia, Latvia, Lithuania, Luxembourg, Malta, Monaco, Netherlands (except non-European territories), Austria, Poland, Portugal, Romania, Sweden, Slovakia, Slovenia, Spain (except Canary Islands, Ceuta + Melilla), Czech Republic, Hungary, Cyprus/Republic (except northern part), including Switzerland
Zone 2 (Europe excluding the EU):
Åland Islands (Finland), Andorra, Albania, Armenia, Azerbaijan, Mount Athos (GR), Bosnia and Herzegovina, Campione d'Italia (IT), Ceuta (E), Faroe Islands (DK), Georgia, Gibraltar (GB), Greenland (DK), Guernsey (GB), Iceland, Jersey (GB), Canary Islands (E), Kazakhstan , Kosovo (Serbian province), Liechtenstein, Livigno (IT), Macedonia, Melilla (E), Moldova (Republic), Montenegro (Republic), Norway, Russian Federation, San Marino, Serbia (Republic), Turkey, Ukraine, Vatican City, Belarus, Cyprus/Republic (northern part)
Zone 3 (World):
Egypt, Algeria, Bahrain, Iran, Iraq, Israel, Yemen, Jordan, Canada, Qatar, Kuwait, Lebanon, Libya, Morocco, Oman, Saudi Arabia, Syria Tunisia, USA, United Arab Emirates
Zone 4 (Rest of the world):
All countries and territories not assigned to Zones 1, 2 or 3.
Please note: We generally deliver worldwide. However, due to differing country regulations, it may be the case that a particular product may not be sold in a specific country (e.g., taurine in Japan).
Delivery times
Unless otherwise stated in the respective offer, delivery of the goods within Germany takes place within 1 - 3 days, and for international deliveries within 3 - 5 days after conclusion of the contract (in the case of agreed advance payment, after the time of your payment instruction).Please note that no deliveries are made on Sundays and public holidays.
If you have ordered items with different delivery times, the goods will be shipped in a single combined shipment, unless we have made different arrangements with you. In this case, the delivery time is determined by the item with the longest delivery time that you have ordered.
Accepted payment methods
- Advance payment by bank transfer- Payment by credit card
- Payment by invoice
Via PayPal Checkout:
- Payment via PayPal
- Payment via PayPal Express
Via PayPal:
- Payment via PayPal
- Payment via PayPal Express
Via Mollie:
- Payment by credit card (via Klarna)
Further details on payment
If you pay by advance payment , we grant you a €2.5 discount on the invoice amount of the order.
Payment by invoice is possible under the following condition :
First orders from new customers/guest customers: total invoice amount max. €200,-
When paying by invoice, the invoice amount must be settled within 14 days.
When paying by credit card, your credit card account will be charged when the goods are shipped.
Our bank details:
Bank details Germany/EU
Deutsche Bank Mannheim/Weinheim
IBAN: DE94 6707 0024 0588 0737 00
BIC: DEUTDEDBMAN
Bank details Switzerland
PostFinance
IBAN: CH42 0900 0000 3026 6470 7
BIC: POFICHBEXXX
For payments via PayPal, please use the following account identifier: info@biotikon.de or via the link: https://paypal.me/biotikon
If you have any questions, you can find our contact details in the legal notice.
Average rating of 5 out of 5 stars
Delivery time 1-3 days
My account
Labels from various OPC or grape seed extract suppliers claim 95% OPC, suggesting that this amount of OPC is obtainable. In general this percentage does not refer to pure OPC, but to OPC grape seed powder,, which may only contain small percentages of OPC. Pure OPC is proanthocyanidins without monomeric proanthocyanidins. OPC is defined differently by various manufacturers and can also be measured with alternate analysis procedures. You should always insist upon seeing an analysis certificate and also pay attention to the analysis method! OPC Plus Certificate of Analysis (click here to view OPC-analysis) German companies like Biotikon® are certifiable. A reliable analysis for the measurement of the OPC content is the RP-HPLC method. In particular we use the RP-HPLC method which is the most commonly used analysis method for high-quality plant materials. Other methods may show different values. A statement of OPC 95% should be critically scrutinized.
OPCplus by Dr. Alexander Michalzik additionally contains high-quality camu camu extract (Camu Camu is the richest vitamin C plant known in science).
Suitable for vegetarians & vegans!
OPC by Dr. Michalzik contains an exceptionally high concentration of OPC (oligomeric procyanidins). Only materials of the highest quality are used. Dr. Michalzik’s OPC contains no fillers (resulting in significantly higher production costs) using only natural substances.
Polyphenols are not just OPC! In addition to 160 mg of OPC (according to RP-HPLC test specifications PV.03.P194 02) other important polyphenols (antioxidant active substances) are included. Test specification is available under www.opc-grapeseedextract.de. According to our company’s philosophy, we leave our OPC in its natural plant compound.
Our product is manufactured in Germany by Biotikon® under supervision of Dr. Michalzik®.
Below you will find several exemplary analysis of grape seed extract used for our OPC products.
In part, these are analyses of recent batches. The analysis value measured with the RP-HPLC method which is always up to date, is the basis for specifying our OPC content. We will gladly send the RP-HPLC analysis to you by mail.
For older batches we used the Vanillin method, Butanol method (Procyanidin-Assay) and Porter Bate-Smith method to compare the OPC methods of measurement.
Suitable for vegetarians & vegans!
RP-HPLC_OPC_Analysezertifkat (click here)
OPC_DMAC (click here to view PAC analysis by DMAC method)
OPC_DMAC (click here to view PAC analysis by DMAC method)
Certificate of Analysis by Vanillin method, Procyanidin-Assay (Butanol method) and the Pharmacopoeia method (EP6.0 1220) (click here)
Biotikon - What makes us Special:
- First company in the world to consistently use no additives in the capsule filling
- Own production for over 20 years
- Owner-managed company based in Germany
- no investment companies
- 40 years of experience in plant science
- Ultra-clean premium extracts of the highest quality
- Capsule shells free of PEG (polyethylene glycol) and carrageenan
- Made in Germany
- Highest standard in food safety: HACCP & ISO 9001
- Sustainable, plastic-free shipping
- Fast delivery
- Own plantation project
- Support of social projects
- Highly professional analysis laboratory
- Team of doctors and alternative practitioners
- Personal advice hotline
Made in Germany
OPCPlus by Dr. Michalzik is subject to strict examinations of German supervisory authorities. It is manufactured by use of gentle production technologies without heat or additives in the capsule filling and without the use of processing agents which are not required to be mentioned on the packaging.
No industrially produced silicic acid (silicon dioxide) flow aid.
Biotikon does not use silicon dioxide or silicic acid
(SiO2, known as E551) as a flow aid.
The foundation for product testing "Stiftung Warentest" states
that those may contain nanoparticles. Silicic acid or silicon dioxide in dietary
supplements has been discouraged.
Bio Suisse has terminated approval
of silica or silicon dioxide. Silica from horsetail is not to be confused with this industrially
produced silica.
No Aluminum Contained
A large number of nutritional supplement providers use aluminum as a sealant for cans.
During the sealing process an aluminum foil is strongly heated by a high frequency electromagnetic field.
We deliberately do not use this method!
Without talcum!
The release agent and lubricant talcum which is used for manufacturing of tablets or capsules can contain
asbestos fibers. Biotikon completely dispenses with the use of release agents and lubricants in their
capsule production.
Fresh Products!
From the date of sale all of our products have a long lasting shelf life. This is possible because we
process in house.
Food Safety HACCP
Biotikon products are manufactured in accordance with legal requirements and in compliance with the
HACCP concept
in order to ensure food safety.
Please note: With each purchase, you are also automatically supporting chosen social projects. Further information can be found in our blog under Social Engagement
OPC is contained in the following products:
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Brain & Mental Performance | |
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Eye Formula | |
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Heart Forte I | |
![]() |
Blood Pressure Regulator | |
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Joint Formula II | |
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Arterial & Blood Vessel Support | |
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Sport - cell protect | |
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Mitochondrium forte / forte PRO |
50 mg
Our OPCplus contains 50 mg of pure camu camu extract per capsule.
Ingredients: Vitis vinifera extract, camu camu extract from Myrciaria dubia, capsule material made of pure vegetable cellulose (Hydroxy-propyl-methyl-cellulose
Purest Quality from Biotikon®
- Pure substances without additives or fillers in the capsule filling
- Gluten-free, lactose-free and gelatine-free
- Information about residue control: please contact us
- Packaging made of HDPE, no plasticisers
- Without animal testing
- We deliver fresh products

1. Plant polyphenols are so-called secondary plant compounds.
2. OPC stands for oligomeric procyanidins. They consist of catechins, which are connected by condensation. This produces substances with a new identity which include a larger range of efficiency than single (= monomeric) catechins. They are called pro- (proantho) cyanidines which at splitting of the compound do not disintegrate into catechins but cyanidins. Green tea for example contains only monomeric (single) catechins, which cannot have the same effect as OPC. A peeled banana will turn brown, iron will rust. The reason is the oxidation of these substances or tissues through radical oxygen molecules (free radicals).
1 -2 OPC plus-capsules.
Package Contents: 72 OPC 160 plus-capsules. Each capsule contains 300 mg grape seed extract and 50 mg camu camu extract.
Storage: Keep cool & dry, protect from light exposure.
When buying OPC products the following criteria should be taken into consideration:
- Documented OPC content with RP-HPLC analysis certificate
- Product should be processed in Germany / German suppliers: Verifiability and security ensured by controllability
- No fillers and additives
- OPC originates from grape seeds. Much knowledge about the product is received from red wine.
| OPC-products from Biotikon® compared | ||||
|---|---|---|---|---|
OPC |
||||
Each capsule contains 300 mg of grape seed extract , daily…
Article details
(€906.06/kg, €0.42/Capsule)
72
Capsules
(€906.06/kg, €0.42/Capsule)
€29.90
|
OPC |
€29.90 (€906.06/kg, €0.42/Capsule) |
Each capsule contains 300 mg of grape seed extract , daily recommendation : 1-2 capsules |
72
Capsules
|
OPC Premium |
||||
Each capsule contains 450 mg of grape seed extract , daily…
Article details
(€867.39/kg, €0.55/Capsule)
72
Capsules
(€867.39/kg, €0.55/Capsule)
€39.90
|
OPC Premium |
€39.90 (€867.39/kg, €0.55/Capsule) |
Each capsule contains 450 mg of grape seed extract , daily dosage : 1 OPC 240 premium capsule |
72
Capsules
|
OPCPlus |
||||
highly active natural antioxidant , each capsule contains 3…
Article details
(€996.97/kg, €0.46/Capsule)
72
Capsules
(€996.97/kg, €0.46/Capsule)
€32.90
|
OPCPlus |
€32.90 (€996.97/kg, €0.46/Capsule) |
highly active natural antioxidant , each capsule contains 300 mg OPC grape seed extract and 40 mg CAMUCAMU extract daily dosage : 1OPC plus capsule |
72
Capsules
|
OPC Premium Plus |
||||
Each capsule contains 450 mg of grape seed extract and 50 m…
Article details
(€932.61/kg, €0.60/Capsule)
72
Capsules
(€932.61/kg, €0.60/Capsule)
€42.90
|
OPC Premium Plus |
€42.90 (€932.61/kg, €0.60/Capsule) |
Each capsule contains 450 mg of grape seed extract and 50 mg Camu Camu extract daily dosage : 1 OPC 240 Premium Plus Capsule |
72
Capsules
|
OPC Premium Piperine PRO |
||||
Each capsule contains 450 mg of grape seed extract , 5 mg P…
Article details
(€921.15/kg, €0.67/Capsule)
72
Capsules
(€921.15/kg, €0.67/Capsule)
€47.90
|
OPC Premium Piperine PRO |
€47.90 (€921.15/kg, €0.67/Capsule) |
Each capsule contains 450 mg of grape seed extract , 5 mg Piperine and 20 mg Phosphatidylcholin , daily dosage : 1 Nativ - OPC 240 premium Piperine PRO Capsule |
72
Capsules
|
OPC from Organic Grapes GOLD |
||||
Each capsule contains 450 mg organic grape seed extract, da…
Article details
(€1,559.38/kg, €0.83/Capsule)
60
Capsules
(€1,559.38/kg, €0.83/Capsule)
€49.90
|
OPC from Organic Grapes GOLD |
€49.90 (€1,559.38/kg, €0.83/Capsule) |
Each capsule contains 450 mg organic grape seed extract, daily serving size: 1 - 2 capsules |
60
Capsules
|
1 of 1 reviews
Average rating of 5 out of 5 stars
5 out of 5 Stars
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1 review
10 January 2026 16:14
Review with rating of 5 out of 5 stars
Perfecto
Excelente servicio al cliente, no tengo ninguna queja y sobre todo les recomiendo el producto a mi me funciona de maravilla
„I recommend you to OPCPlus following products:”
OPCPlus is often purchased together with:
Your Biotikon®Advantages
Quality
- Made in Germany
- Premium-quality extract
- Aluminum-free seal
- Capsule contains no additives*

Shipping
- Environmentally-friendly dispatch packaging
- free shipping on orders over 70 Euro in EU countries, UK & switzerland
- with
also on packing stations,
3 - 5 days
1 - 3 days-
3 - 5 days
We are here for you
Mo. to Fr.:8 a.m. till 7 p.m. Sa.: 9 a.m. till 4 p.m.All contact options
Payment
- On account (by invoice)

Security
- Secure purchase by means of a buyer seal certification from the trade association "Händlerbund". Info
- Secure Data Transfer 128 bit SSL encryption


















