Food supplement
with OPC and vitamin C

OPC Premium according to Dr. med. Michalzik is made from French grapes.

Was ist echtes OPC? Dr. med. Alexander Michalzik und Dr. rer. nat. Klaus Denzel im Gespräch

Dr. rer. nat. Klaus Denzel erkärt die unterschiedlichen Messmethoden für den Gehalt an OPC (Oligomere Proanthocyanidine) bei Nahrungsergänzungsmitteln. Polyphenolgehalt ist nicht gleich OPC-Gehalt. Auch monomere oder polymere Proanthocyanidine sollten nicht zu den OPCs gerechnet werden.

You get 720 mg OPC per euro, or 720,000 mcg OPC per euro (320,000 mcg per capsule). Compare this value. We do not count monomers as OPC. There are providers who write, "highest purity per capsule worldwide: 60,000 mcg". However, this is only 60 mg per capsule. "Native OPC premium according to Dr. med. Michalzik" is a tested OPC product. The verified high content of pure OPC in the grape seed extract gives the customer confidence that where it says OPC, it really is OPC.

"OPC 95 - the strongest antioxidant in the world. Perhaps the best OPC in the world"—that is an advertising slogan used by competing providers. They also claim: "Unbeatable price-performance ratio". Let’s take a closer look: The provider refers to OPC 95. This designation is also used by raw material suppliers who promise 95% OPC but, when asked, usually do not test the OPC content and instead mostly test only the polyphenols. This is a major difference! Likewise, for example, it is declared "105 mg OPC per capsule". At 95% OPC, this would be 110.5 mg grape seed extract per capsule. However, the OPC content is not verified by an analysis. With a similar provider from Switzerland, despite a claim of 300 mg OPC, we were only able to find 5 mg in the analysis. It is not stated where the grapes come from. Often, grape seeds grown in China are used. The prices are then extremely low. By comparison: Biotikon has 450 mg grape seed extract per capsule, i.e., 4 times as much. The OPC content of 320 mg is based on analyses; the analysis is published. The grape seeds come from France.

Conclusion: On closer inspection, the cheaper product does not always have a better price-performance ratio.

OPC 300 mg: This advertising promise is made by competitors with only 300 mg grape seed extract content. The OPC content would then have to be 100%. Here, grape seed extract is equated with OPC content.

OPC 95%: The designation OPC 95 is used by many manufacturers to describe their OPC quality, but as a rule indicates a lower OPC quality. Usually, it does not mean the OPC content, but rather the analysis value according to "Bate Smith", which indicates ratio values and is not suitable for measuring OPC precisely. Or it refers to the polyphenol content. This means that OPC 95% does not mean that it contains 95% OPC. If you buy OPC, ask for the original certificate of analysis from a German independent analytical institute that states the OPC content.

OPC 400 mg, 450 mg, 500 mg: Here too, you should make sure that this is not the capsule weight, but how high the actual OPC content is.

OPC analysis, OPC verification

OPC is a substance recognized worldwide, but few have mastered the complex topic of OPC analysis. The OPC certificate of analysis should always state OPC. What matters is the OPC content verified by grape seed extract analyses. Have the OPC content confirmed by a German certificate of analysis from a German laboratory. The provider’s location in Germany is also important, as in some other countries proof is sometimes not required.

OPC according to Dr. med. Michaltik also contains vitamin C. This contributes to:

• normal collagen formation for the normal function of cartilage, bones, blood vessels, gums, teeth and skin
• normal function of the nervous system and psychological function
• protecting cells from oxidative stress
• the reduction of tiredness and fatigue
• normal energy-yielding metabolism
• normal function of the immune system

Quality features

of OPC premium Dr. med. Michalzik

• 320 mg OPC in the special grape seed extract Dr. med. Michalzik, measured using the RP-HPLC method (test specification PV.03.P194_02). OPCs are proanthocyanidins. Monomeric proanthocyanidins are not counted towards the OPC capsule content. The test specification can be viewed at www.opc-traubenkernextrakt.de.
• 450 mg special grape seed extract per capsule
  

Ingredients per daily serving, 1 - (2) capsules:

• 450 (900) mg grape seed extract (OPC special grape seed extract according to Dr. med. Michalzik)
  320 (640) mg pure, genuine OPC
  OPC are proanthocyanidins excluding the monomeric proanthocyanidins. Measured using the RP-HPLC method test specification PV.03.P194_2. Test specification available at www.opc-traubenkernextrakt.de. Verified by mass spectrometry (MS) and diode array detection (DAD).
  
  
• 50 (100) mg pure vitamin C**

** corresponds to 62.5 (125) % of the reference amount (NRV) for daily intake according to the LMIV

450 (900) mg grape seed extract contain 320 (640) mg OPC measured directly in the extract for improved accuracy. (Test specification PV.03.P194_2. OPC are proanthocyanidins minus the monomeric proanthocyanidins. Verified by MS and DAD (see above).

In contrast to many other OPC products, due to the exceptionally high OPC content, in normal circumstances 1 capsule per day is sufficient for intake.

Active substances:

• Polyphenols (see diagram) 95 %
• OPC content 320 (640) mg in the grape seed extract (Test specification PV.03.P194_02 available at www.opc-traubenkernextrakt.de. OPC are proanthocyanidins without monomeric PAC (proanthocyanidins). Verified by MS and DAD.
• Other polyphenols such as catechins, epicatechin, quercetin, etc.

Ingredients: Extract from Vitis vinfera (grape seed extract), capsule shell hydroxy- propyl methyl cellulose***, vitamin C (ascorbic acid)

*** made from plant cellulose

Recommended intake:
Adults take 1–2 capsules per day after a meal.

Pack contents:
90 OPC premium capsules, each capsule contains 450 mg grape seed extract.