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69517 Gorxheimertal
+49 (0)6201-878380
What is authentic OPC? Dr. Alexander Michalzik and Dr. rer. nat. Klaus Denzel in conversation
Dr rer. Nat. Klaus Denzel explains the different measuring methods for the content of OPC (oligomeric proanthocyanidins) in food supplements. Polyphenol content is not the same as the OPC content. Also, monomeric or polymeric proanthocyanidins should not be included in OPCs.
OPCplus by Dr. Alexander Michalzik additionally contains high-quality camu camu extract (Camu Camu is the richest vitamin C plant known in science).
Suitable for vegetarians & vegans!
OPC by Dr. Michalzik contains an exceptionally high concentration of OPC (oligomeric procyanidins). Only materials of the highest quality are used. Dr. Michalzik’s OPC contains no fillers (resulting in significantly higher production costs) using only natural substances.
Polyphenols are not just OPC! In addition to 160 mg of OPC (according to RP-HPLC test specifications PV.03.P194 02) other important polyphenols (antioxidant active substances) are included. Test specification is available under www.opc-grapeseedextract.de. According to our company’s philosophy, we leave our OPC in its natural plant compound.
Our product is manufactured in Germany by Biotikon® under supervision of Dr. Michalzik®.
Below you will find several exemplary analysis of grape seed extract used for our OPC products.
In part, these are analyses of recent batches. The analysis value measured with the RP-HPLC method which is always up to date, is the basis for specifying our OPC content. We will gladly send the RP-HPLC analysis to you by mail.
For older batches we used the Vanillin method, Butanol method (Procyanidin-Assay) and Porter Bate-Smith method to compare the OPC methods of measurement.
Suitable for vegetarians & vegans!
RP-HPLC_OPC_Analysezertifkat (click here)
OPC_DMAC (click here to view PAC analysis by DMAC method)
OPC_DMAC (click here to view PAC analysis by DMAC method)
Certificate of Analysis by Vanillin method, Procyanidin-Assay (Butanol method) and the Pharmacopoeia method (EP6.0 1220) (click here)


Made in Germany.
OPCPlus by Dr. Michalzik is subject to strict examinations of German supervisory authorities. It is manufactured by use of gentle production technologies without heat or additives in the capsule filling and without the use of processing agents which are not required to be mentioned on the packaging.
Biotikon does not use silicon dioxide or silicic acid (SiO2, known as E551) as a flow aid. The foundation for product testing "Stiftung Warentest" states that those may contain nanoparticles. Silicic acid or silicon dioxide in dietary supplements has been discouraged. Bio Suisse has terminated approval of silica or silicon dioxide. Silica from horsetail is not to be confused with this industrially produced silica.
A large number of nutritional supplement providers use aluminum as a sealant for cans. During the sealing process an aluminum foil is strongly heated by a high frequency electromagnetic field. We deliberately do not use this method!
The release agent and lubricant talcum which is used for manufacturing of tablets or capsules can contain asbestos fibers. Biotikon completely dispenses with the use of release agents and lubricants in their capsule production.
From the date of sale all of our products have a long lasting shelf life. This is possible because we process in house.
Biotikon products are manufactured in accordance with legal requirements and in compliance with the HACCP concept











OPC is contained in the following products:

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Brain & Mental Performance | |
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Eye Formula | |
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Heart Forte I | |
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Blood Pressure Regulator | |
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Joint Formula II | |
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Arterial & Blood Vessel Support | |
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Sport - cell protect | |
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Mitochondrium forte / forte PRO |
50 mg
Our OPCplus contains 50 mg of pure camu camu extract per capsule.
Ingredients: Vitis vinifera extract, camu camu extract from Myrciaria dubia, capsule material made of pure vegetable cellulose (Hydroxy-propyl-methyl-cellulose
Purest Quality from Biotikon®
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Pure substances without additives or fillers in the capsule filling |
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Gluten-free, lactose-free and gelatine-free |
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Information about residue control: please contact us |
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Packaging made of HDPE, no plasticisers |
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Without animal testing |
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We deliver fresh products |

1. Plant polyphenols are so-called secondary plant compounds.
2. OPC stands for oligomeric procyanidins. They consist of catechins, which are connected by condensation. This produces substances with a new identity which include a larger range of efficiency than single (= monomeric) catechins. They are called pro- (proantho) cyanidines which at splitting of the compound do not disintegrate into catechins but cyanidins. Green tea for example contains only monomeric (single) catechins, which cannot have the same effect as OPC. A peeled banana will turn brown, iron will rust. The reason is the oxidation of these substances or tissues through radical oxygen molecules (free radicals).
1 -2 OPC plus-capsules.
Package Contents: 72 OPC 160 plus-capsules. Each capsule contains 300 mg grape seed extract and 50 mg camu camu extract.
Storage: Keep cool & dry, protect from light exposure.
Important Note: The recommended daily dose should not be exceeded. Nutritional supplements are not intended to be a substitute for a varied and balanced diet or a healthy lifestyle. Children, pregnant women, and nursing mothers should consult with a doctor before using this product. Keep out of reach of children.When buying OPC products the following criteria should be taken into consideration:
- Documented OPC content with RP-HPLC analysis certificate
- Product should be processed in Germany / German suppliers: Verifiability and security ensured by controllability
- No fillers and additives
- OPC originates from grape seeds. Much knowledge about the product is received from red wine.
OPC-products from Biotikon® compared | ||||
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29,90 € |
300 mg of OPC Premium Grape Seed Extract per capsule by Dr. Michalzik, M.D. with at least 160 mg of pure OPC* |
72 Capsules |
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OPCPlus |
32,90 € |
300 mg of OPC Premium Grape Seed Extract per capsule by Dr. Michalzik and Camu Camu extract with at least 160 mg of pure OPC* |
72 Capsules |
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OPC Premium |
39,90 € |
450 mg of OPC Premium Grape Seed Extract per capsule by Dr. Michalzik, M.D. with at least 240 mg of pure OPC* |
72 Capsules |
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OPC Premium Plus |
42,90 € |
450 mg of OPC Premium Grape Seed Extract per capsule by Dr. Michalzik, M.D. with Camu Camu extract and at least 240 mg of pure OPC* |
72 Capsules |
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OPC Premium Piperine PRO |
47,90 € |
450 mg of OPC premium grape seed extract per capsule by Dr. Michalzik, containing Piperine and phosphatidylcholine with at least 240 mg of pure OPC* |
72 Capsules |
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OPC from Organic Grapes |
59,90 € |
- currently not available |
60 Capsules |
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OPC GOLD from Organic Grapes |
99,90 € |
- currently not available |
60 Capsules |
OPCPlus
is often purchased together with:
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Quality
- Made in Germany
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- Capsule contains
no additives*
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